2016年1月7日星期四

IgA nephritis diagnosis

IgA nephritis diagnosis on how much you know? A lot of people do not know, if you are interested in this issue, we ask you to follow the experts with questions together a detailed look at it.

IgA nephritis is a special type of glomerulonephritis, children and adolescents is a high risk of IgA nephritis, IgA nephritis itself is an immune system, good treatment of IgA nephritis do first premise is the differential diagnosis of patients with IgA nephritis, good diagnostic IgA nephritis is very important, the correct diagnosis can help patients with timely treatment.

IgA nephritis Differential Diagnosis:

First, acute glomerulonephritis after streptococcal infection

Should exhibit acute nephritic syndrome of IgA nephropathy with identification, the former long incubation period, self-healing tendencies; the latter a short incubation period, repeated illness, combined with laboratory tests (such as C3, ASO) can be funded distinction.

Second, thin basement membrane nephropathy

Often persistent microscopic hematuria, often a positive family history of hematuria, renal biopsy shows IgA negative electron microscope diffuse thinning of the glomerular basement membrane. Generally difficult to identify.

Third, the secondary IgA deposition mainly glomerulopathy

Allergic purpura renal pathology and immunopathology with IgA nephropathy same, but the former are often typical of renal manifestations, such as skin purpura, joint pain, abdominal pain and melena, etc., can be identified.

Chronic alcoholic cirrhosis 50% ∽90% of renal tissues of patients with alcoholic cirrhosis can be displayed in the main immunoglobulin IgA deposition, but only a very small number of patients with clinical manifestations of renal involvement. Identification and IgA nephropathy mainly based on the presence of cirrhosis.

Lupus nephritis immunofluorescence mostly full house (IgG, IgA, IgM, C3, C1q, fibrin related antigen were positive). In addition, multi-system involvement of systemic lupus erythematosus clinical features and immunological tests help to identify.

After reading the above description, for the differential diagnosis of IgA nephritis You are clear yet, if you are for that matter, what would like to know please feel free to consult our experts online.

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