Iga nephropathy causes what

Currently, Iga nephropathy incidence in our lives is very high, as long as the treatment of glomerulonephritis timely usually no big problem, but regardless of whether if it would have extremely serious consequences. Then lead to the cause of glomerulonephritis and what it?

Experts pointed out: Iga nephropathy is associated with varying degrees of proteinuria, with recurrent gross hematuria, microscopic hematuria or immunoglobulin deposition Iga mainly characterized by kidney disease.

Currently, the pathogenesis of Iga nephropathy yet entirely clear, therefore, causes Iga often difficult to trace, however, Iga nephropathy belongs to immune complex glomerular disease caused by this reason is more agreeable to reason.

One reason: the immune system:

IgA nephropathy is characterized by deposition of Iga in glomerular kidney disease, immune system due Iga led to the emergence of the deposition mesangial area in the circulatory system.

Two reasons: the bone concerned:

Glomerular mesangial deposition of Iga, and is present in the blood Iga-1 similar to the hinge region glycosylation abnormalities, suggesting deposition in kidney patients Iga Iga mesangial area of ​​bone marrow-derived Iga.

Three reasons: the cytokines:

Iga nephropathy patients mesangial deposition of Iga-1 caused by mesangial cells secrete inflammatory factors.

These are the main cause of Iga nephropathy, patients want to have a certain significance. Iga nephropathy patients in understanding the causes of kidney disease, be sure to promptly go to a regular hospital for examination and treatment to prevent disease progression, prognosis.


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