In Nephrology, people is probably the deepest impression nephritis, and the highest incidence of this disease, may nephritis there are many, such as IGA nephropathy, a disease of the body in the end what is the harm? And how is suffering from the disease treatment? A lot of people want to know, here we come to see.
iga nephropathy treatment principles? A lot of people experience this disease will know what to do, do not know how to do good, in fact, just find professional treatment hospital good protective measures, the stringent requirements of a doctor's guidance can still do well to alleviate disease .
So far, no satisfactory treatment of this disease. Diseases associated with renal dysfunction in patients using corticosteroids or immunosuppressive no progress is inconsistent. Recent data show that more than 1g / d urine protein, improve the proteinuria beneficial adrenocorticotropic hormone administration. Minimal change nephropathy IgA antibody deposition may reduce proteinuria. Cyclophosphamide in combination with dipyridamole and warfarin can reduce proteinuria and no effect on glomerular filtration rate; cyclosporin A can reduce urinary protein used in combination, can also be reduced creatinine clearance. Phenytoin, antiplatelet effects, anthocyanin glycosides within the sodium diphenyl hydantoin drugs can not be determined.
Although there are reports of urokinase to protect the glomerular filtration rate, but it is very important. Recurrent tonsillitis, tonsillectomy in infection prevention and therapeutic benefit; antibiotics may acute nephritic syndrome and acute renal failure showed some help. Observed a small series, fish oil may reduce proteinuria and glomerular filtration rate function.
iga nephropathy treatment principles? immunoglobulin IgA nephropathy serious (glomerular filtration rate 2 ~ 4ml / min monthly decline) high-dose intravenous gamma globulin can prevent the glomerular filtration rate, improve hematuria and proteinuria, But after treatment, often relapse. Severe hypertension and proteinuria, using converting enzyme inhibitors can delay the glomerular filtration rate, reduce the rate of protein in the urine, so serious immunoglobulin IgA nephropathy, converting enzyme inhibitor is an anti-hypertensive drugs first choice. Inhibitors effectively is not clear that the conversion of normal blood pressure.
Immunoglobulin IgA nephropathy with end-stage renal transplantation reception, soon mesangial deposition of IgA antibody; if there are subclinical immunoglobulin IgA nephropathy kidney donors, non-IgA nephropathy in uremic patients immune deposits, mesangial area usually disappear quickly. After the kidney transplant is not necessarily a kidney transplant with an immunoglobulin IgA nephropathy relapse progressive renal failure, but the application of immunosuppressive therapy, including cyclosporine A did not stop its development. Cadaveric renal transplantation, 1-year and 3-year graft survival was 87% and 77%, however, immunoglobulin IgA kidney transplantation antigens HLA individuals IgA antibodies 2 year graft survival rate was 100%, and there is sufficient reason to believe that these antibodies, HLA antigens increase the beneficial effects of graft survival.
Xiaobian to introduce the principle of treatment iga nephritis, after you read, it should now be clear, once symptoms appear, you best to the regular professional hospital to check, symptomatic treatment, in addition to the daily diet care is also very important thing, I hope the above help to you.
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