Ⅰ, vasodilators: Why is it due to vasodilator after IGA immune complexes stimulate the capillaries cause kidney mesangial cell ischemia and hypoxia, vasodilators purpose is to improve renal blood circulation, relieve renal ischemia and hypoxia each resident cells? state, for the next fix mesangial cells provide a good environment.
Ⅱ, degradation: glomerular capillary increase in inflammatory cells and blood vessels in the micro-thrombosis, and immune complex deposition IGA, sediment accumulation and extracellular matrix causes glomerular mesangial cells increased, So we must continue to use the drugs degrade extracellular matrix deposition of these excreted in the urine, avoid glomerulosclerosis.
Ⅲ, anticoagulation: an increase in inflammatory cells in the blood, blood viscosity will increase to some extent, which increases the glomerular capillary micro thrombosis. The use of anticoagulant drugs is to prevent the formation of micro-thrombi maintain blood flow, further lay the foundation for mesangial cell repair.
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